Hundreds protested Donald Trump in New York and blocked a major road in the southwestern state of Arizona, where a demonstrator was punched and kicked at a rally.

The latest attempts by opponents to disrupt the campaign of the top US Republican White House hopeful resulted in a handful of arrests, police and witnesses said.

In Tucson, Arizona a protester with a sign showing Trump ' s face and the words " Bad For America, " was kicked and punched by a member of the audience while being escorted out of the venue by security, video posted online by NBC showed.

The network reported that the audience member was handcuffed and taken away before being charged with assault with injury, according to police.

Meanwhile, on the other side of the country, demonstrators who gathered at Manhattan ' s Columbus Circle, near one of the billionaire real estate mogul ' s luxury buildings overlooking Central Park, shouted the slogan " Donald Trump, go away, racist, sexist, anti - gay. "

Amid a considerable police presence, protesters held up signs that read " Deport Trump " and " Build a wall around Trump. "

Also spotted in the crowd were placards which read " Don ' t let bigotry Trump our constitution " and " Will trade 1 Donald Trump for 25,000 refugees. "

At least one person was arrested on the city ' s famous Fifth Avenue during a brief skirmish that was quickly brought under control by police.

The demonstration was organized by a group called Cosmopolitan Antifascists, with others joining in.