The Israeli suspects were arrested early on Sunday over the death of 16 - year - old Muhammad Abu Khdeir.
They have admitted to kidnapping the Palestinian teen from a neighborhood of East al - Quds and then beating and burning him to death.
Palestinian sources said on Saturday that postmortem examination findings have shown that Abu Khdeir was burned alive and hit with a blunt object on the head.
The brutal killing of the Palestinian teenager has sparked a wave of protests across the occupied territories.
New video footage has also emerged showing masked Israeli forces brutally beating a Palestinian - American teenager in East al - Quds while in police custody.
The 15 - year - old boy has been identified as Tariq Abu Khdeir, the cousin of Mohammed Abu Khdeir.
In reaction to recent crimes against Palestinians, the acting president of the Palestinian national unity government, Mahmoud Abbas, called on Sunday for an international investigation into crimes committed against Palestinians.
According to the latest figures revealed by the Palestinian Ministry of Information in Ramallah, Israeli forces have killed one Palestinian kid in every three days for the past 13 years. Based on the same source, nearly 1,500 children have been killed during the Second Intifada, or popular uprising, between 2000 and 2013.